Polymorphic DQ alpha and DQ beta interactions dictate HLA class II determinants of allo-recognition.
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چکیده
منابع مشابه
Polymorphic DQ alpha and DQ beta interactions dictate HLA class II determinants of allo-recognition
18 transfected cell lines were generated that expressed distinct DQ molecules related to the serologically defined HLA-DQw3 specificity. These transfectants were constructed using site-directed mutagenesis to introduce nucleotide substitutions into DQ3.2 beta cDNA, followed by retrovirus-mediated gene expression of the mutagenized genes in human B cell lines with different endogenous DQ alpha c...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1990
ISSN: 0022-1007,1540-9538
DOI: 10.1084/jem.171.1.85